Pig Health: Controlling PMWS and PDNS

Pig Health: Controlling PMWS and PDNS

Practical methods for controlling PMWS

To date, the introduction of Viramatrix fortified feed rations from weaning is having a noticeably beneficial effect. Coupled with the treatment of individual sick pigs with serotherapy, "huge" improvements are being reported by the unit manager. A word of caution however, the critical period is approaching and over the next few weeks we will see a more complete picture - but things are looking up!

Serotherapy: Work in serotherapy has been reported from both Spain and France. In the UK, Jake Waddilove and a few others are trying this approach. Initial results look promising, however, Jake has warned that this procedure is controversial. Strict veterinary supervision is required and the serum collected for a farm MUST come from pigs on that farm to ensure the Medicines Act is not contravened.

We are being specifically vague on this process at present as work is ongoing by Jake Waddilove and Mike Muirhead to develop an agreed protocol for the procedure. This is being treated as a matter of urgency and we will keep everyone updated as things progress. In the meantime please discuss any questions you may have with your Veterinary Surgeon.

Immuno enhancers - Feed supplements: A clinical observation study is underway with one of the most promising feed supplements (Viramatrix) which is high in natural antioxidants, and although it is early days (the pigs are 8 weeks old), the pigs fed the supplement are looking exteremly fit and healthy and are currently not showing any typical early PMWS signs. Only time will tell!

Three Golden rules for controlling PMWS

Based on our latest knowledge of these two diseases, this article puts forward three golden rules for controlling PMWS, and attempts to provides a structured basis for introducing a farm based action plan to help control the serious problems the diseases cause.

At the conference the debate ranged from what was, and just as important, what was not known about the disease and its association with the PCV2 virus, what research was needed, through to what can be done at a the farm level to help mitigate some of the consequences of the disease. This article concentrates on the latter of these.

ThePigSite.com attended the conference and in conjunction with one of our consultants, Mike Muirhead, have summarised the KEY elements that have been used at farm level and found to help the situation. These are a mixture of the 20 Madec principles, development of these principles, and some other ideas that arose from the discussions.

The list of factors presented have been broken down into three categories, with the aim of providing a clear set of action points. However it is important to note nearly all the points can be split into just three golden rules. If you always keep these 3 rules in mind and make efforts to follow their intent, you'll be on the right track.

Three Golden rules for controlling PMWS
Rule 1 Limit pig-to-pig contact. The virus is spread around the farm by pig-to-pig contact. Limit pig-to-pig contact and you will limit the prevalence of the disease. REMEMBER pig-to-pig contact can also be INDIRECT by a needle, surgical instrument, muck or people. Spread can often be to many pigs in a pen or in large common groups etc.
Rule 2 "Stress" is a killer. Stressed animals are far more likely to become diseased. This includes not only obvious physical stress factors but also exposure to micro organisms which cause major stress to the immune system. If the immune system is overactivated, the PCV2 virus may produce disease, unless there is a good colostral antibody. THINK - If a procedure causes the pigs to become stressed, ask "can this be done in a less stressful manner?".
Rule 3 Good Hygiene There is no substitute for good hygiene and biosecurity measures. Clean, disinfected buildings, clean instruments and good hygiene will all make a difference. Don't spread disease by needle or other instruments.

With these 3 key rules in mind, we have listed the specific actions, that can be taken at farm level to help mitigate the affects of the disease.

To help with implementation we have broken these points down into three categories:

  1. Management practises you should aspire to do.
  2. Management practises you should try to achieve.
  3. Additional things that have been reported to help.

Start with the top list, focusing on a few items at a time. Once these are in place move onto the second list, actioning a few items at a time. Always bear in mind the 3 golden rules and ensure everyone's actions meet their intent.

Things you should aspire to
  Action Explanation Reason/Benefits
1 Farm-wide
All-in, all-out is King. Apply across the farm. If not by building, by enclosed pen
Strictly apply these procedures. For it to be successful all-in, all-out means just that. There are no half measures. It is vital it is done properly. Rule 1: The virus appears to pass from pig to pig. The application of all-in, all-out helps limit this risk, however it only works if it is practised fully and used in-conjunction with the next point.
2 Farm-wide
Apply strict Cleaning and Disinfection procedures.
Hygiene standards are absolutely critical. Wet down pens using detergent, Leave for as long as possible to soak, Powerwash off ALL accessible organic material, Disinfect with Virkon S (or other suitable disinfectant) per instructions. Allow to dry. Rule 3: The virus survives in waste organic matter. If pens are not fully cleaned and disinfected disease can be passed down the line. Use Virkon S as it is reported to be the most effective solution for killing the PCV2 virus. Micro-organisms need water to live, where ever possible allow pens to dry out before re-stocking.
3 Farm-wide
Limit the mixing of pigs to an absolute minimum
As best as possible, try to maintain pig groups from weaning through to finishing. Rule 1,2: Mixing pigs breaks two rules. It increases pig-to-pig contact and places the pigs under stress, both of which appear to significantly increase the prevalence of the disease.
4 Farrowing
Good colostrum management
Colostral immunity would appear to exist, therefore it is vital that piglets get a good colostrum intake ideally within the first 6 hours of birth, but certainly within 24 hours. Any procedures to enhance colostrum intake need to be taken within 24 hours of birth. Do not cross foster after this period (see next point)
5 Farrowing
Stop Cross-fostering after 24 hours.
In the first 24 hours piglets are receiving colostrum and any immunity is high. Once colostrum intake stops the immunity status of the piglets is fixed. Rule 1: Cross fostering of piglets after 24 hours may help spread the virus. This should be avoided where possible. If this procedure needs to be used, set up a cull sow in a separate house/area specifically for this purpose.
6 W-G-F
Solid Partitions between pens
Where pens of pigs are separated by open barriers, these should ideally be changed to solid barriers. Rule 1: Open partitions allow pig to pig contact. This allows the spread of the virus increasing the likelihood of disease. Barriers should be designed to prevent nose-to-nose contact between pigs.
7 W-G-F
Lower stocking densities
The following stocking densities are recommended by Madec:
Weaners: 3 pigs/sq.m.
Grow/Finish: + 0.75 sq.m/pig
Rule 2: The lower the stocking density the less the pigs are stressed. Less stress equals healthier pigs.
W-G-F = Weaner, Grower and Finisher accommodation


Other things you should try to achieve:
8 Weaners
Increase access to feeders
The pigs should have plenty of room to access feeders. Madec recommends at least 7cm per piglet. Rule 2: If piglet have to fight for food, this will increase the stress levels. Greater access lowers the need to fight for food, lowering stress.
9 W-G-F
Improved temperature control
Limit the temperature variation the pigs are exposed to. Ideally the temperature should allow the pigs to be comfortable at all times. Rule 2: Chilling causes stress, lowers immunity and increases the risk of infection.
10 W-G-F
Reduce pen sizes.
Madec recommends a pen size of around 13 pigs, or that of one litter. Rule 1,2: This may or may not practical depending upon your building layout, but the fewer number of pigs in a pen, fewer pigs can be infected in any given group.
11 Farrowing
Stop teeth clipping
Stop clipping teeth and free up some time to action some of the other points. Rule 1: Is it really necessary to clip teeth these days? This only helps spread the disease. Many producers are reported to have stopped. Why not give it a try! Alternatively, action as below.
12 Farm-wide
Implement strict hygiene measures
Ensure good hygiene standards when injecting and tail docking. Use new needles, sterilise instruments etc. Rule 1,3: What better way to spread disease than by injecting numerous pigs with the same needle! It has been suggested that needles and instruments be dipped in a 2% solution of Virkon S for 60 seconds between pigs to kill the virus. Have a number of instruments on the go, all stored in Virkon S, and rotate the instruments as you treat each pig.
13 Farrow-W-G-F
Vaccination and Vaccination timing
Three types of vaccination were discussed: M-hyo. Glässers and PRRS. Any affects should be monitored. The timing of vaccination should also be reviewed. Avoid vaccinating piglets around the time of weaning, apply, say one week before or after. Rule 2,3: Vaccination was implicated as a trigger for the disease on some farms, but on others vaccination had not been used. It was considered the timing of the M-hyo vaccination might be important on some farms, but if respiratory problems existed it was considered better to continue. It was suggested the Glässers vaccine could be more beneficial than not, and the view was the PRRS vaccines had little effect on the disease (PMWS), but helped to increase growth rates. Both weaning and vaccination stress the piglets thus doing both together can cause excessive stress which should be avoided.
14 Farm-wide
Prompt removal of sick pigs
Move sick pigs promptly to the hospital pen. Rule 1: The longer sick pigs are left in the pen the greater the likelihood that other pigs in the pen will become sick.
15 Farm-wide
Formalise a "Sick Pig" policy
Formalise your policy on what you will do with sick pigs in the hospital pen. Write it down and follow it to the letter. You should be clear on when a pig should be euthanased or how long it will be given to "recover". There is nothing more demoralising than poorly pigs not getting any better. Be clear and decide what to do with them. It will help staff morale.
16 Farm-wide
Good "disposal" of dead pigs
Do not leave dead pigs uncovered. Remove to a remote area of the farm and cover over with straw pending disposal. The sight of dead pigs is very disturbing to staff and will not help morale. They act as a constant reminder of the problems.
W-G-F = Weaner, Grower and Finisher accommodation


Other ideas that have been reported to have a positive effect
17 W-G-F
Improve air quality
Madec recommends the following limits:
NH3 < 10ppm,
CO2 < 0.15%
Improving the air quality is beneficial because it reduces the development of respiratory disease
18 W-G-F
Sensible flow within buildings (air, animals)
Improving air flow within a building will help to reduce toxic gases Rule 2: This helps reduce the stress on the respiratory system
19 Sows
Feedback
This principle is based on exposing sows to the pathogen, to increase colostral immunity which is then passed on to the piglets. One option is to feed back grower faeces to pregnant sows between 80 - 90 days gestation. This may or may not be successful, and could make things worst. Discuss this with your veterinarian.
20 Farrowing
Improved nutrition
The use of immuno-enhancer feed products have been reported to help, however data as to their effectiveness is limited. One product (Vira Matrix) was reported as having shown good results. Immuno-enhancers are designed to enhance the ability of the pigs immune system to resist attack from a pathogen. It was also reported that feeding vegetables (dried carrots) to suckling piglets could help.
21 Farrowing
Treat sows/gilts for parasites before farrowing
Give sows/gilts a good wash and treat for parasites before they enter the farrowing house Rule 2: Parasitic burdens on the sow result in the animal becoming disadvantaged or in poor condition. In this state its colostrum levels might be compromised having a detrimental effect on the piglets. In a well managed herd this should not be an issue.
22 Finishing-Farrowing
Serology
Injecting piglets with a serum created from older healthy pigs who have been through the system. There are several complications with this, not least the legality of doing it. However, it was reported this procedure had appeared to be beneficial in Spanish trials, and could be something you might wish to discuss with your veterinarian.
23 W-F-G
Aerial Disinfection
Aerial disinfection using Virkon S or other suitable disinfectant) may have an affect on reducing the spread of the virus. Rule 3: There was little information on the effectiveness of aerial disinfection, but a number of producers are trying it. We will endeavour to follow up on this as these trials progress.
24 W-F-G
Water disinfection
Disinfection of the water reduces the micro-organism challenge presented to the pigs and improves hygiene. Rule 2,3: Less challenge, less stress.
W-G-F = Weaner, Grower and Finisher accommodation

 


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